![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/06/GW604714X-is-a-Potent-Inhibitor-of-Mitochondrial-Respiration-2021-06-08.jpg)
The transport of pyruvate into the mitochondria plays an important role in glucose oxidation, lipogenesis, and gluconeogenesis. It is also…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/03/MID-1-is-a-Disruptor-of-MG53-IRS-1-Interaction-2021-03-09.jpg)
Noninsulin-dependent diabetes mellitus (type 2 diabetes) is becoming an epidemic disease due to the increased incidence of obesity. Mitsugumin 53…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/07/KPLH1130-is-a-Pyruvate-Dehydrogenase-Kinase-Inhibitor-Against-Inflammatory-Disease-2019-07-08.jpg)
Macrophage polarization is a process by which macrophages carry out various functional programs responding to signals. Pyruvate Dehydrogenase Kinase (PDK)…