![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/02/GSK-J4-is-a-Dual-Inhibitor-of-H3K27me3-me2-Demethylases-JMJD3-KDM6B-and-UTX-KDM6A-2021-02-18.jpg)
H3K27me3 is an epigenetic modification of DNA packaging protein histone H3. Specifically, it is a marker for the trimethylation of…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/02/BMS-986202-is-an-Orally-Active-Tyk2-Inhibitor-that-Binds-to-Tyk2-JH2-2021-02-06.jpg)
Tyrosine kinase 2 (Tyk2) is a non-receptor tyrosine kinase belonging to the Janus kinase (JAK) family. Specifically, the mammalian JAK…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/01/CU-115-is-a-Selective-TLR8-Antagonist-2021-02-03.jpg)
Nucleic acid (NA) sensors are part of the innate immune system. they can recognize multiple forms of intracellular self and…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/01/BMS-753-is-a-Selective-RARα-Agonist-2020-02-02.jpg)
RARs (α，β, and γ and their isoforms) and RXRs (α，β, and γ and their isoforms) are members of the nuclear…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/01/LY-311727-is-a-Secretory-non-Pancreatic-Phospholipase-A2-sPLA2-Inhibitor-2021-01-28.jpg)
Phospholipase A2 (PLA2s) is an enzyme that cleaves fatty acids in the second position of phospholipids. Specifically, PLA2s can specifically…