CXC chemokine receptors are the complete membrane proteins and they can specifically bind and respond to CXC chemokine family cytokines. Specifically, they represent a subfamily of chemokine receptors, a large…
CXCR-4 is an α-chemokine receptor specific for SDF-1, which is a molecule with the strong chemotactic activity of lymphocytes. Specifically, CXCR-4 is a receptor of stromal cell-derived factor-1 α and…
Histone deacetylases (HDAC) are a class of enzymes that remove acetyl groups from an ε-N-acetyl-lysine amino acid on a histone. Specifically, selective HDAC inhibitors are as a potential anti latent…
The human immunodeficiency viruses (HIV) are two species of Lentivirus that infect humans. It causes acquired immunodeficiency syndrome (AIDS). Besides, AIDS is a condition in which progressive failure of the…
The BAF (mammalian SWI/SNF) chromatin remodeling complex establishs and maintains viral latency. In particular, BAF (SWI/SNF) is an attractive target for HIV-1 latency reversal. In this study, researchers report a…