![](https://www.Immune-System-Research.com/"wp-content/uploads"/2022/05/Aplaviroc-IS-A-CCR5-INHIBITOR-2022-0508.png)
Aplaviroc (AK 602), an SDP derivative, is a potent CCR5 antagonist. Additionally, the IC50s are 0.1-0.4 nM for HIV-1Ba-L, HIV-1JRFL, and…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2022/01/Rottlerin-is-a-Specific-PKC-Inhibitor-2022-01-07.jpg)
Protein kinase C (PKC) is a family of protein kinase enzymes with 15 isoforms that can regulate the protein function.…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/09/Nelfinavir-AG-1341-is-an-Orally-Active-HIV-1-Protease-Inhibitor-2021-09-25.jpg)
HIV protease is a homodimeric aspartyl protease. It is worth noting that, HIV protease is crucial for the viral life-cycle.…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/12/Cobicistat-is-a-Selective-CYP3A-Inhibitor-and-a-Pharmacokinetic-Enhancer-of-HIV-Inhibitors-2020-12-22.jpg)
The highly active antiretroviral therapy (HAART) can transform the human immunodeficiency virus (HIV) infection into a manageable chronic disease in…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/08/TC14012-is-a-Selective-CXCR4-Inverse-Agonist-and-CXCR7-Agonist-2020-08-19.jpg)
CXC chemokine receptors are the complete membrane proteins and they can specifically bind and respond to CXC chemokine family cytokines.…