![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/09/Nelfinavir-AG-1341-is-an-Orally-Active-HIV-1-Protease-Inhibitor-2021-09-25.jpg)
HIV protease is a homodimeric aspartyl protease. It is worth noting that, HIV protease is crucial for the viral life-cycle.…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/12/Cobicistat-is-a-Selective-CYP3A-Inhibitor-and-a-Pharmacokinetic-Enhancer-of-HIV-Inhibitors-2020-12-22.jpg)
The highly active antiretroviral therapy (HAART) can transform the human immunodeficiency virus (HIV) infection into a manageable chronic disease in…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/08/TC14012-is-a-Selective-CXCR4-Inverse-Agonist-and-CXCR7-Agonist-2020-08-19.jpg)
CXC chemokine receptors are the complete membrane proteins and they can specifically bind and respond to CXC chemokine family cytokines.…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/07/The-Potent-CXCR4-Antagonist-KRH-3955-Is-an-Orally-Bioavailable-Inhibitor-of-HIV-1-2020-07-18.jpg)
CXCR-4 is an α-chemokine receptor specific for SDF-1, which is a molecule with the strong chemotactic activity of lymphocytes. Specifically,…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/04/BRD3308-a-Highly-Selective-HDAC3-Inhibitor-Activates-HIV-1-Transcription-and-Disrupts-HIV-1-Latency-2020-05-02.jpg){kind=spacer}
Histone deacetylases (HDAC) are a class of enzymes that remove acetyl groups from an ε-N-acetyl-lysine amino acid on a histone.…