Aplaviroc (AK 602), an SDP derivative, is a potent CCR5 antagonist. Additionally, the IC50s are 0.1-0.4 nM for HIV-1Ba-L, HIV-1JRFL, and…
Protein kinase C (PKC) is a family of protein kinase enzymes with 15 isoforms that can regulate the protein function.…
HIV protease is a homodimeric aspartyl protease. It is worth noting that, HIV protease is crucial for the viral life-cycle.…
The highly active antiretroviral therapy (HAART) can transform the human immunodeficiency virus (HIV) infection into a manageable chronic disease in…
CXC chemokine receptors are the complete membrane proteins and they can specifically bind and respond to CXC chemokine family cytokines.…