Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Symptoms typically include fever, cough, headache, fatigue, difficulty breathing, and loss of smell…
The angiotensin II receptors are a class of G protein-coupled receptors with angiotensin II as their ligands. Angiotensin II receptors include four subtypes: AT1, AT2, AT3 and AT4. They are…
HIV is a virus that affects the immune system. HIV infects important cells in the human immune system, such as helper T cells (especially CD4+T cells), macrophages, and dendritic cells.…
REV-ERB is a member of the nuclear receptor (NR) superfamily of intracellular transcription factors. Besides, REV-ERB also is a key regulatory component of the circadian clock. Meanwhile, REV-ERB regulates the…
5-HT1A receptor is a subtype of 5-HT receptors that bind 5-HT. It is a G protein-coupled receptor that can couple to Gi proteins. In the brain, 5-HT1A activation mediates hyperpolarization…
Interleukin-2 (IL-2) is a cytokine from activated T cells. IL-2 plays a critical function in the generation, differentiation, survival, and homeostasis of immune effector cells. Moreover, IL-2 functions to expand…
Histamine H4 Receptor (H4R) is a member of the G protein-coupled receptor superfamily. Besides, H4R involves in mediating eosinophil shape change and mast cell chemotaxis. Importantly, H4R mRNA and protein…
Bruton tyrosine kinase (BTK) is a non-receptor kinase and plays a crucial role in carcinogenic signal transduction. Carcinogenic signal transduction is crucial for the proliferation and survival of leukemia cells…
Phospholipase is a member of a very complex group of enzymes that break down phospholipids into fatty acids and other compounds. Phospholipase is defined by the enzymatic reaction they catalyze.…
Coronavirus is a single-stranded righteous RNA virus as well as an enveloped virus. It consists of alpha coronaviruses (α-CoV), beta coronaviruses (β-CoV), gamma coronaviruses (γ-CoV) and delta coronaviruses (δ-CoV). Specifically,…