Glycine transporters (GlyTs) are the Na+/Cl–-dependent plasmalemmal neurotransmitter transporters. GlyTs comprise GlyT1 and GlyT2. They serve to terminate the signaling…
Phosphodiesterases (PDEs) are enzymes that catalyze the hydrolysis of the 3′ cyclic phosphate bond of cyclic nucleotides. PDEs can break…
Nociceptin, as a 17-amino acid peptide, is a potent endogenous agonist for the opiate receptor-like orphan receptor (ORL-1). It exhibits…
Phosphatidylinositol-4-phosphate 5-kinase type-1C (PIP5K1C) is a lipid kinase that regulates focal adhesion dynamics and cell attachment through the site-specific formation…