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The clinical use of tetracycline has a long history, dating back to 1948. And Tetracycline antibiotics are sought after because…
Degradation of proteins in mammalian cells via two distinct pathways: lysosome-dependent and proteasome-dependent. PR-39 is a proline- and arginine-rich antibacterial peptide.…
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Nosocomial infections can lead to mortality. They account for approximately 2 million patients per year in the United States. Gram-negative…
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SpCas9 is an RNA-guided DNA endonuclease and has a facile introduction of genomic alterations. The SpCas9 complex and guide RNA…
The current treatment of bacterial infections is challenged by a dramatic increase of multidrug-resistant (MDR) strains. In addition to Gram-negative…