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Category: Bacterial

PR-39, an Antibacterial Peptide, is a Noncompetitive and Allosteric Proteasome Inhibitor

PR-39, an Antibacterial Peptide, is a Noncompetitive and Allosteric Proteasome Inhibitor

Degradation of proteins in mammalian cells via two distinct pathways: lysosome-dependent and proteasome-dependent. PR-39 is a proline- and arginine-rich antibacterial peptide. It is also a noncompetitive, reversible, and allosteric proteasome inhibitor. PR-39 reversibly binds…

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