Degradation of proteins in mammalian cells via two distinct pathways: lysosome-dependent and proteasome-dependent. PR-39 is a proline- and arginine-rich antibacterial peptide.…
Nosocomial infections can lead to mortality. They account for approximately 2 million patients per year in the United States. Gram-negative…
SpCas9 is an RNA-guided DNA endonuclease and has a facile introduction of genomic alterations. The SpCas9 complex and guide RNA…
The current treatment of bacterial infections is challenged by a dramatic increase of multidrug-resistant (MDR) strains. In addition to Gram-negative…
Staphylococcus aureus is a major bacterial human pathogen that causes a wide variety of clinical manifestations. Staphylococcus aureus is the…