Exceptional developments in combination antiretroviral therapy (cART) have transformed HIV/AIDS from a deadly pandemic to chronic and manageable disease. HIV-1 capsid (CA) has two structurally distinct domains, an N-terminal domain…
Human immunodeficiency virus (HIV) is a threat to humans and a serious issue for public health worldwide. Especially, acquired immune deficiency syndrome (AIDS) is the most serious stage of HIV…
In previous blog “MLT-747, an Allosteric MALT1 Inhibitor for Immunodeficiency Research”, we introduced MLT-747 as a potent, selective, allosteric inhibitor of MALT1, which could rescue function in an immune deficient…
Immunodeficiency is a state, in which the immune system’s ability is absent. It is not able to fight against cancer or infectious diseases. MALT1 is the human paracaspase, with the…