HIV-1 protease (PR) is a retrovirus aspartyl protease (retropepsin), an enzyme involved in the hydrolysis of retroviral peptide bonds that is critical to the life cycle of HIV, the retrovirus…
Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) is a strain of coronavirus that causes COVID-19 (coronavirus disease 2019), the respiratory illness responsible for the COVID-19 pandemic. Although different small-molecule therapeutics…
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the COVID-19 pandemic. Firstly, the coronavirus 3-chymotrypsin-like protease (3CLpro) can control virus replication. Secondly, 3CLpro is responsible for cleaving…
Coronavirus disease 2019 (COVID-19) has caused a huge threat to global public health. Moreover, the constant emergence of variants of concern (VOCs) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)…
As we all know, the SARS-CoV-1 virus caused the 2002-2004 SARS outbreak. Today, we will introduce a virus -- SARS-CoV-2. SARS-CoV-2 is related to the SARS-CoV-1 virus. SARS-CoV-2 belongs to…
Coronaviruses are a diverse group of viruses infecting many different animals, and they can cause mild to severe respiratory infections. In 2002 and 2012, respectively, two highly pathogenic coronaviruses with…
SARS-CoV-2 is a positive-sense single-stranded RNA coronavirus. This virus can cause severe acute respiratory syndrome and spreads between people through aerosols and respiratory droplets. It broke out in early 2020,…
COVID-19 is an infectious disease caused by the coronavirus (SARS-CoV-2), which mainly causes symptoms such as fever and cough. It spreads through droplet transmission or contact transmission. Since 2019, COVID-19…
SARS-CoV-2 is a positive-sense single-stranded RNA coronavirus. This virus can cause severe acute respiratory syndrome and spreads between people through aerosols and respiratory droplets. It broke out in early 2020,…
Methisazone (Marboran) is a compound of the class of N-aminomethyl-isatin-beta-thiosemicarbizones. It acts as an antiviral agent, working via inhibiting mRNA and protein synthesis. In the early 1950s, Methisazone has been found to…