![](https://www.Immune-System-Research.com/"wp-content/uploads"/2023/05/PRE-084-is-a-S1R-Agonist-for-Cardiovascular-and-Neurological-Disease-Research-20230524.jpg)
The sigma-1 receptor (σ1R， S1R), one of two sigma receptor subtypes, is a chaperone protein at the endoplasmic reticulum (ER)…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2023/04/LY456236-is-an-Orally-Active-mGlu1-Receptor-Antagonist-for-Neurological-Disease-2023-0425.jpg)
Epilepsy is one of the most common neurological diseases in the world. Firstly, Epilepsy affects people of all ages, races,…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2023/03/JNJ-56022486-is-an-Orally-Active-Negative-AMPA-Receptor-Modulator-for-Epilepsy-Research-2023-0307.png)
Glutamate is the primary excitatory neurotransmitter in the mammalian brain. AMPA (α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionic acid) is the subtype of glutamate receptors and…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2023/02/Fuzapladib-IS-741-is-A-Potent-Phospholipase-A2-Inhibitor-2023-0216.jpg)
Phospholipase is a member of a very complex group of enzymes that break down phospholipids into fatty acids and other…
Glycine transporters (GlyTs) are the Na+/Cl–-dependent plasmalemmal neurotransmitter transporters. GlyTs comprise GlyT1 and GlyT2. They serve to terminate the signaling…