![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/09/Cyclosporin-A-an-Immunosuppressant-Binds-to-the-Cyclophilin-and-Inhibits-Calcineurin-Phosphatase-Activity-2021-09-09.jpg)
Immunosuppressive agents, also known as immunosuppressants and antirejection medications, can inhibit or prevent activity of the immune system. Immunosuppression is…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/12/CC-92480-is-a-Cereblon-E3-Ubiquitin-Ligase-Modulating-Drug-with-Antimyeloma-Activity-2019-12-10.jpg)
Immunomodulatory agents (IMiDs) are a class of immunomodulatory drugs. Thalidomide analogs have induced significant antimyeloma effects via immune-modulation, antiangiogenesis, and…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/11/GNF362-is-a-Highly-Selective-and-Orally-Active-Itpkb-Inhibitor-2019-12-3.jpg)
In mature lymphocytes, the Spatio-temporal regulation of Ca2+ modulates signaling pathways. They serve to control a variety of cellular responses, such…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/12/PF-06651600-is-a-Orally-Active-and-Covalent-JAK3-Selective-Inhibitor-2019-12-2.jpg)
JAK/STAT-dependent cytokines are essential for the development, proliferation, and function of T-cells. The JAK family of nonreceptor tyrosine kinases is…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/11/PD-407824-is-a-Dual-Chk1-and-WEE1-Inhibitor-2019-11-31.jpg)
Bone morphogenetic proteins (BMPs) are important regulators of embryonic development and stem cell fate decisions. In human ESCs, BMP4 promotes…