HCV Archives - Immune System Research

BI-1230 is a Digit Nanomolar HCV NS3 Protease and Viral Replication Inhibitor

2020-02-19 Edward Jenner

BI-1230 is a potent and digit nanomolar inhibitor of HCV NS3 protease and of viral replication. BI-1230 is also highly selective against other serine/cysteine proteases. It also shows good Pharmacokinetic(PK)…

MK-0608 is an Orally Active Inhibitor of HCV Replication

2019-11-24 Edward Jenner

Hepatitis C virus (HCV) infection is a major cause of chronic liver disease and associated morbidity and mortality worldwide. HCV associates with an increased incidence of liver fibrosis, cirrhosis, and…

PF-4878691 is a Selective TLR7 Agonist with HCV Antiviral Efficacy

2019-11-03 Edward Jenner

Chronic hepatitis C (CHC) virus infection continues to be a significant health burden, and 2–3% of the global population infected by the hepatitis C virus (HCV). The innate immune response…

Immune System Research

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