The major cause of the chronic liver disease is the Hepatitis C virus (HCV). HCV is able to establish a chronic infection that may lead to liver fibrosis, liver cirrhosis,…
Enteroviruses comprise several pathogens. They cause a large variety of clinical manifestations that range from mild illnesses to more serious or even life-threatening diseases. They include meningitis, encephalitis, myocarditis, pancreatitis, acute…
RNA virus represents an enormous public health problem. Although drug therapy is essential to mitigate the significant morbidity and mortality associated with these viruses, the number of antiviral drugs is…
BI-1230 is a potent and digit nanomolar inhibitor of HCV NS3 protease and of viral replication. BI-1230 is also highly selective against other serine/cysteine proteases. It also shows good Pharmacokinetic(PK)…
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease and associated morbidity and mortality worldwide. HCV associates with an increased incidence of liver fibrosis, cirrhosis, and…