NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls the transcription of DNA, cytokine production and cell survival. Moreover, NF-κB is present in virtually all…
Osteoarthritis (OA) is a major global health burden. Osteoarthritis becomes an increasingly greater threat to human well-being at present. P2Y receptors are G-protein-coupled receptors (GPCRs) for extracellular nucleotides. There are…
NADPH oxidase (nicotinamide adenine dinucleotide phosphate oxidase; Nox) is a membrane-bound enzyme complex, which faces extracellular space. It catalyzes the production of superoxide free radical through transferring an electron from…