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Category: Osteoporosis

NF157 is a Highly Selective Nanomolar P2Y11 Antagonist

2020-02-04 Edward Jenner

Osteoarthritis (OA) is a major global health burden. Osteoarthritis becomes an increasingly greater threat to human well-being at present. P2Y…

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Posted in: Osteoporosis Filed under: P2Y11, TNF-α

APX-115 is an Orally Active pan-Nox Inhibitor

2019-09-13 Edward Jenner

NADPH oxidase (nicotinamide adenine dinucleotide phosphate oxidase; Nox) is a membrane-bound enzyme complex, which faces extracellular space. It catalyzes the…

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Posted in: Diabetic Complication, Kidney Fibrosis, Kidney Injury, Osteoporosis Filed under: Mitochondria, Nox, Peroxisome

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