Remibrutinib is an Orally Active BTK Inhibitor for Chronic Urticaria Research
Remibrutinib is a potent and orally active BTK inhibitor for Chronic urticaria (CU) research.
Remibrutinib is a potent and orally active BTK inhibitor for Chronic urticaria (CU) research.
On November 15, 2023, the U.S. Food and Drug Administration has approved Defencath (taurolidine and heparin) catheter lock solution (CLS). CLS can reduce the incidence of catheter-related bloodstream infections in…
Dopamine Receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS). The neurotransmitter dopamine is the primary endogenous ligand for dopamine receptors.…
5-HT receptors, 5-hydroxytryptamine receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems. They mediate both excitatory…
Tubulointerstitial fibrosis is a chronic and progressive process affecting kidneys during aging and in chronic kidney disease (CKD). The US Centers for Disease Control and Prevention project that 47% of…
Duchenne muscular dystrophy (DMD) is a genetic muscle disease. And The feature is contraction-induced myofibre injury and inflammation. Besides, researchers found that NF-κB signaling is active in dystrophin deficient muscle.…
Factor XIa (FXIa) is a serine protease involved in the coagulation cascade. Moreover, FXI knockout mice were found to be protected from arterial and venous thrombosis. Therefore, that FXIa inhibition…
Interleukin-12 (IL-12) is a receptor for IL-12R and belongs to the type I cytokine receptor family, subfamily 4. This cytokine acts as a growth factor for activated T and NK…
Fungicides accounts for the majority of pesticide application which are extensively used to fight fungal parasites. Azole fungicides are a family of highly effective systemic fungicides that act by inhibiting…
Immune-mediated necrotising myopathies (IMNM) belongs to idiopathic inflammatory myopathies (IIMs) which encompass a group of acquired muscle disorders. Including dermatomyositis, inclusion body myositis, polymyositis and overlap myositis. However, IMNM are…