![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/06/Secukinumab-AIN457-is-a-Human-Monoclonal-Antibody-Targeted-against-IL-17A-2021-06-26.jpg)
Interleukin-17 family (IL-17 family) is a pro-inflammatory cystine node cytokine family. After binding to the receptor, IL-17 can activate several…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/03/LEO-39652-is-a-Dual-Soft-PDE4-Inhibitor-2021-03-18.jpg)
Atopic dermatitis (AD) is a chronic inflammatory skin disease. the characterizes of AD are eczematous lesions and intense itching. The…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/02/BMS-986202-is-an-Orally-Active-Tyk2-Inhibitor-that-Binds-to-Tyk2-JH2-2021-02-06.jpg)
Tyrosine kinase 2 (Tyk2) is a non-receptor tyrosine kinase belonging to the Janus kinase (JAK) family. Specifically, the mammalian JAK…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/07/BMS-986251-is-an-Orally-Active-and-Selective-RORγt-Inverse-Agonist-2020-07-07.jpg)
Retinoic acid-related orphan receptor γt (RORγt) is a nuclear hormone receptor (NHR) and belongs to the RORγ family. It exists…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/03/CCG-203971-is-a-Second-Generation-RhoA-MRTF-A-Inhibitor-with-Antifibrotic-Effect-2020-03-21.jpg)
Metastasis is the major driver in cancer-related deaths. Metastases involve dysregulation of numerous cellular processes. Importantly, blockade of RhoC prevents…