As previously introduced, we all have known that RRx-001, a hypoxia-selective epigenetic agent and a radio- and chem-sensitizer. Additionally, it…
The blockade of the PD-1/PD-L1 immune checkpoint pathway with monoclonal antibodies has provided significant advances in cancer therapy. However, the…
Programmed death protein 1 (PD-1) is a major immunological checkpoint that belongs to the CD28 family. Importantly, it has an…
In cancer treatment, checkpoint inhibition of adaptive immunity is an important breakthrough of epoch-making significance. However, this therapy doesn’t work…