CD6, a surface glycoprotein of T cells, is a rheostat-type signalosome that tunes T cell activation. It belongs to the…
The Janus kinase (JAK) family of protein-tyrosine kinase has four members: JAK1, JAK2, JAK3, and TYK2. The Janus kinases share…
The bombesin (Bn) receptor family includes the gastrin-releasing peptide (GRPR) and neuromedin B (NMBR) receptors, Bn receptor subtype 3 (BRS-3)…
Phosphoinositide 3-kinases (PI3Ks) are a family of enzymes that catalyze the phosphorylation of the 3-hydroxyl position of the inositol ring.…
Janus kinases (JAKs) are cytoplasmic tyrosine kinases. JAKs link cytokine signaling from membrane receptors to signal transducer and activator of…