p38 mitogen-activated protein kinase (MAPK) plays a key role in cellular response, proliferation, survival, cell cycle and cancer migration. Moreover, the…
PI3Kδ is a lipid kinase mainly expressed in hematopoietic cells and responsible for key signal transduction in cells of the…
Janus kinase (JAK) is a family of intracellular, nonreceptor tyrosine kinases. The JAK family is composed of four cytoplasmic tyrosine…
CD6, a surface glycoprotein of T cells, is a rheostat-type signalosome that tunes T cell activation. It belongs to the…
The Janus kinase (JAK) family of protein-tyrosine kinase has four members: JAK1, JAK2, JAK3, and TYK2. The Janus kinases share…