![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/04/MK-0812-is-a-Selective-CCR2-Antagonist-2021-05-12.jpg)
Inhibition of monocyte and macrophage function by targeting chemokine receptors represents an attractive strategy for therapeutic intervention in inflammatory diseases.…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/04/NDMC101-is-a-Potent-Osteoclastogenesis-Inhibitor-2021-04-24.jpg)
Bone is a complex tissue that contains various types of cells. There exist two major cell types responsible for bone…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/02/UCB-9260-Inhibits-TNF-Signalling-by-Stabilising-an-Asymmetric-form-of-the-Trimer-2021-02-10.jpg)
Tumor necrosis factor (TNF) is a cytokine belonging to a family of trimeric proteins. This factor acts as a key…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/01/GSK620-is-a-Potent-and-Orally-Active-pan-BET-BD2-Inhibitor-2020-01-08.jpg)
The therapeutic potential of extra terminal domain inhibitor (iBET) has increasing studies both in oncology and immunoinflammatory. Moreover, iBETs are…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/12/HS271-is-a-Highly-Potent-Orally-Active-and-Selective-IRAK4-Inhibitor-2020-12-24.jpg)
IRAK-4 (interleukin-1 receptor-associated kinase 4) is a protein kinase involved in signal transduction of innate immune response from toll-like receptors.…