![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/07/Baricitinib-LY3009104-is-a-Selective-and-Orally-Active-JAK1-and-JAK2-Inhibitor-2021-07-12.jpg)
Janus kinases (JAKs) are cytoplasmic tyrosine kinases. JAKs link cytokine signaling from membrane receptors to signal transducer and activator of…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/06/BMS-587101-is-an-Orally-Active-Antagonist-of-LFA-1-2021-06-12.jpg)
Leukocyte function-associated antigen-1 (LFA-1), also known as CD11a/CD18 and αLβ2, is a member of the β2-integrin family found on lymphocytes…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/04/MK-0812-is-a-Selective-CCR2-Antagonist-2021-05-12.jpg)
Inhibition of monocyte and macrophage function by targeting chemokine receptors represents an attractive strategy for therapeutic intervention in inflammatory diseases.…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/04/NDMC101-is-a-Potent-Osteoclastogenesis-Inhibitor-2021-04-24.jpg)
Bone is a complex tissue that contains various types of cells. There exist two major cell types responsible for bone…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/02/UCB-9260-Inhibits-TNF-Signalling-by-Stabilising-an-Asymmetric-form-of-the-Trimer-2021-02-10.jpg)
Tumor necrosis factor (TNF) is a cytokine belonging to a family of trimeric proteins. This factor acts as a key…