Tumor necrosis factor (TNF) is a cytokine belonging to a family of trimeric proteins. This factor acts as a key…
The therapeutic potential of extra terminal domain inhibitor (iBET) has increasing studies both in oncology and immunoinflammatory. Moreover, iBETs are…
IRAK-4 (interleukin-1 receptor-associated kinase 4) is a protein kinase involved in signal transduction of innate immune response from toll-like receptors.…
Nuclear factor-κB (NF-κB) represents a family of inducible transcription factors. The transcription factor NF-κB regulates multiple aspects of innate and…
Proinflammatory stimuli induce rapid transcriptional responses. They are essential for host defense from infection. An inflammatory response involves a variety…