![](https://www.Immune-System-Research.com/"wp-content/uploads"/2022/11/22.11.24-GDC-2394-NLRP3-inhibitor.jpg)
Nucleotide oligomerization domain (NOD)-like receptors (NLRs) are critical cytoplasmic pattern-recognition receptors (PRRs) that play an important role in the host’s…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2022/09/TAK-676.jpg)
Stimulator of interferon genes (STING), an integral ER-membrane protein, is a protein that in humans is encoded by the STING1…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2022/08/T16Ainh-C01-is-An-TMEM-Inhibitor-2022-0811.jpg)
Calcium-activated chloride channels (CaCCs) are always expressed in epithelial and nonepithelial cells. They are involved in epithelial fluid secretion, sensory…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/11/SEW2871-is-a-Highly-Selective-and-Orally-Active-S1P1-Agonist-2019-11-07.jpg)
G protein-coupled receptors (GPCRs) are also known as 7TM receptors due to their transmembrane domains. they constitute the largest superfamily…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/09/C-178-is-a-Covalent-Small-Molecule-Inhibitor-of-STING-2019-09-26.jpg)
In the previous blog, I have introduced C-176 as a strong and covalent mouse STING inhibitor. Today, I’d like to…