![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/11/iKIX1-Inhibits-the-Interaction-of-the-CgGal11A-KIX-Domain-and-the-CgPdr1-Activation-Domain-2020-11-10.jpg)
iKIX1 is an anti-fungal agent and re-sensitizes drug-resistant C. glabrata to azole antifungals in vitro. In HepG2 cells, iKIX1 inhibits…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/04/ME1111-an-Antifungal-Agent-and-Succinate-Dehydrogenase-Inhibitor-has-the-Potential-to-Treat-Onychomycosis-2020-04-23.jpg)
Onychomycosis is an infection of the nail plate that is prevalent among the ageing population. Onychomycosis is difficult to treat…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/04/Neticonazole-is-a-Long-Acting-Antifungal-Agent-and-an-Orally-Active-Exosome-Secretion-Inhibitor-2020-04-09.jpg)
Exosomes act as vesicles of endosomal origin secreted from reticulocytes. Exosomes bear proteins, lipids, and RNAs, mediating intercellular communication between…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/01/SSF-109-is-a-Broad-Spectrum-Fungicide-by-Inhibiting-the-Ergosterol-Biosynthesis-2020-01-02.jpg)
The mevalonate pathway consists of a series of enzymes in mammalian cells. Those enzymes can transform acetyl-Coenzyme-A (CoA) to cholesterol…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/12/Fosmanogepix-is-an-Orally-Active-Gwt1-Inhibitor-with-Antifungal-Activity-2019-12-11.jpg)
Invasive pulmonary aspergillosis (IPA) is the leading cause of mold infections in the immunocompromised host. Despite the current aggressive antifungal…