iKIX1 is an anti-fungal agent and re-sensitizes drug-resistant C. glabrata to azole antifungals in vitro. In HepG2 cells, iKIX1 inhibits…
Onychomycosis is an infection of the nail plate that is prevalent among the ageing population. Onychomycosis is difficult to treat…
Exosomes act as vesicles of endosomal origin secreted from reticulocytes. Exosomes bear proteins, lipids, and RNAs, mediating intercellular communication between…
The mevalonate pathway consists of a series of enzymes in mammalian cells. Those enzymes can transform acetyl-Coenzyme-A (CoA) to cholesterol…
Invasive pulmonary aspergillosis (IPA) is the leading cause of mold infections in the immunocompromised host. Despite the current aggressive antifungal…