CD40 (cluster of differentiation 40) is a costimulatory protein found on antigen-presenting cells (APC). Its receptor belongs to the TNF-receptor superfamily and is important for immune and inflammatory responses, including…
Immunosuppressants that prevents acute rejection has dramatically improved graft survival in organ transplantation. For instance, calcineurin inhibitors (CNIs) improve the survival of patients receiving transplants. However, CNIs also cause adverse…
Organ transplantation is a common medical procedure and helps the recipient to replace a damaged or missing organ. But the procedure is quite challenging, because of immune responses. Medicines for…