Lupus, technically known as systemic lupus erythematosus (SLE), is an autoimmune disease, characterized by polyclonal B-cell proliferation and a variety…
Interferons (IFNs) are a kind of cytokines, which is used for communication between cells to trigger the protective defenses of…
Toll-like receptors 7 and 8 (TLR7/8) are receptors for single-stranded RNA that reside in the endosome. TLR8 mainly expresses in…
Tyrosine kinase 2 (Tyk2) is a non-receptor tyrosine kinase belonging to the Janus kinase (JAK) family. Specifically, the mammalian JAK…
Janus kinases are non-receptor tyrosine kinases. In mammals, the family has four members, Jak1, Jak2, Jak3 and Tyrosine kinase 2…