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Category: Intestinal Inflammation

ZED-1227 is an Orally Active and Specific Transglutaminase 2 Inhibitor for Intestinal Inflammation

ZED-1227 is an Orally Active and Specific Transglutaminase 2 Inhibitor for Intestinal Inflammation

Transglutaminases (TG) belong to a family of structurally and functionally related enzymes. These enzymes catalyse Ca2+-dependent post-translational modifications of proteins. Of these, Transglutaminase 2 (TG2) is an inducible transamidating acyltransferase…

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