![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/02/WEHI-9625-a-VDAC2-BAK-Interaction-Enhancer-Blocks-mBAK-Mediated-Apoptosis-2021-02-25.jpg)
Much of the past effort has focused on targeting caspases, proteases that mediate many of the hallmarks of apoptotic cell…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/01/SBP-7455-is-an-Orally-Active-Dual-ULK1-ULK2-Autophagy-Inhibitor-2020-01-23.jpg)
Autophagy is a multi-step pathway initiated through the ULK preinitiation complex, which consists of unc-51-like autophagy activating kinase 1 (ULK1)…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/01/KMH-233-is-a-Reversible-and-Selective-LAT1-Inhibitor-2020-01-18.jpg)
Amino acids are essential for protein synthesis, they are supporting cell growth, and metabolism. System L belongs to the family…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/01/Osimertinib-is-an-Irreversible-and-Mutant-Selective-EGFR-Inhibitor-2020-01-13.jpg)
Epidermal growth factor receptor (EGFR) is a transmembrane receptor tyrosine kinase protein. EGFR plays an important role in controlling cell…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/12/CB-5083-is-a-Selective-and-Orally-Bioavailable-p97-Inhibitor-2020-12-17.jpg)
The AAA+ ATPase p97 is essential to a wide range of cellular functions. The p97 acts downstream from ubiquitin signaling…