Much of the past effort has focused on targeting caspases, proteases that mediate many of the hallmarks of apoptotic cell…
Autophagy is a multi-step pathway initiated through the ULK preinitiation complex, which consists of unc-51-like autophagy activating kinase 1 (ULK1)…
Amino acids are essential for protein synthesis, they are supporting cell growth, and metabolism. System L belongs to the family…
Epidermal growth factor receptor (EGFR) is a transmembrane receptor tyrosine kinase protein. EGFR plays an important role in controlling cell…
The AAA+ ATPase p97 is essential to a wide range of cellular functions. The p97 acts downstream from ubiquitin signaling…