SARS-CoV-2 is a positive-sense single-stranded RNA coronavirus. This virus can cause severe acute respiratory syndrome and spreads between people through aerosols and respiratory droplets. It broke out in early 2020,…
HIV-1 integrase (IN) is an enzyme responsible for integrating the viral DNA copy of the viral RNA genome into the host chromatin. Specifically, IN is one of the main anti-virus…
Spns2 (Sphingolipid Transporter 2) is a non-ATP dependent S1P (sphingosine-1-phosphate) transporter, that transports S1P from endothelial and lymph-endothelial cells, and regulates S1P concentration in plasma and lymph. Particularly, Sphingosine 1-phosphate…
Glycine transporters (GlyTs) are the Na+/Cl--dependent plasmalemmal neurotransmitter transporters. GlyTs comprise GlyT1 and GlyT2. They serve to terminate the signaling of glycine by mediating its reuptake from the synaptic cleft…
Oxytocin Receptor, also known as OXTR, OTR, is the receptor protein for oxytocin and is encoded by the OTR gene located on human chromosome 3p25. OTR protein belongs to the…
CFTR (Cystic fibrosis transmembrane conductance regulator), mutations of which cause cystic fibrosis, belongs to the ATP-binding cassette (ABC) transporter family. Transitions between open and closed states of CFTR are regulated…
Histamine receptors are a type of G protein-coupled receptor (GPCR), including four subtypes: H1, H2, H3, and H4 receptors. They have different functions. For example, the H1 receptor regulates circadian…
Muscarinic receptor, also known as muscarinic cholinergic/acetylcholine receptor (mAChR), belongs to the G protein-coupled receptor (GPCR) family and is found in many parts of the body, such as brain and…