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Category: Rhinitis

PF-03654764 is a Selective Histamine H3 Receptor Antagonist

2020-07-29 Edward Jenner

The symptoms of Allergic rhinitis are rhinorrhea, sneezing, nasal pruritus, congestion, and aggravation of comorbid asthma. Histamine can interact with…

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Posted in: Allergy, Rhinitis Filed under: H3, Histamine

CAY10471 is a Selective and Orally Active CRTH2 Antagonist

2020-05-07 Edward Jenner

CAY10471 (TM30089) is a potent, selective, and orally active prostaglandin D2 receptor CRTH2 antagonist. In PC12 cells, CAY10471 blocks 15d-PGJ2-induced…

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Posted in: Allergy, Asthma, Fibrosis, Kidney Fibrosis, Rhinitis Filed under: CHS, CRTH2, Prostaglandin
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5-HT Anti-Inflammatory Anti-Tumor Antibacterial Antimalarial Antitumor Antiviral Apoptosis Autophagy Breast Cancer Chemokines COPD COVID-19 Cytokine EGFR HBV HCV HDAC HIV IFN IL-6 IL-17 Infection Integrin Interferon Interleukin IPF JAK Leukemia Low Toxicity Multidrug Resistance Necroptosis NF-κB p38 MAPK PPI Proteasome RIPK STAT STING T Cell Th17 TLR TNF TNF-α α4β1
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