![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/06/PMX-53-is-an-Orally-Active-Complement-C5a-Receptor-Antagonist-2020-06-09.jpg)
C5a is an important inflammatory hypernociceptive mediator, acting by a mechanism independent of hypernociceptive cytokine release, but dependent on the…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/03/MK-0429-Oral-Integrin-αβ3-Inhibitor-Kidney-Fibrosis-Complement-2019-04-11.jpg)
Integrins are cell surface protein receptors with α and β subunits. They participate in multiple cellular functions such as adhesion…