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Category: Schizophrenia

BI-425809 is a Selective and Orally Active GlyT1 Inhibitor

2021-07-15 Edward Jenner

Glycine transporters (GlyTs) are plasmalemmal neurotransmitter transporters. GlyTs, which regulate brain glycine levels, is an inhibitory neurotransmitter with co-agonist activity…

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Posted in: Alzheimer, Neurological Disease, Schizophrenia Filed under: CSF, GlyT1

SEP-363856 is an Orally Active Psychotropic Agent with a non-D2/5-HT2A Action

2021-04-27 Edward Jenner

Antipsychotics are a class of medication for managing psychosis, principally in schizophreniabut also in a range of other psychotic disorders.…

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Posted in: Parkinson’s, Schizophrenia Filed under: 5-HT, Antipsychotic, TAAR1
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5-HT Anti-Inflammatory Anti-Tumor Antibacterial Antimalarial Antitumor Antiviral Apoptosis Autophagy Breast Cancer Chemokines COPD COVID-19 Cytokine Dopamine EGFR ER Stress HBV HCV HDAC HIV IFN IL-6 IL-17 Infection Inflammasome Integrin Interleukin IPF JAK Leukemia Low Toxicity Multidrug Resistance NF-κB p38 MAPK PI3K PPI Proteasome RIPK ROS T Cell Th17 TLR TNF TNF-α
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