mGluR (metabotropic glutamate receptor) is a type of glutamate receptor that are active through an indirect metabotropic process. They are members of thegroup C family of G-protein-coupled receptors, or GPCRs.…
A number of evidence indicate that the serotonin (5-hydroxytryptamine, 5-HT) system participates in memory formation. Additionally, recent reviews provide further support to the notion that 5-HT1 to 5-HT4 and 5-HT6…
Quipazine is a nonselective 5-HT receptors agonist. 5-HT receptors (Serotonin receptors) are a group of G protein-coupled receptors (GPCRs) and ligand-gated ion channels (LGICs) found in the central and peripheral…
CaMKII (Ca2+/calmodulin-dependent protein kinase II) is an oligomeric protein kinase assembled by 12−14 monomers in a double-layered ring. Structurally, each monomer consists of an N-terminal catalytic domain, a self-regulatory domain…
Glycine transporters (GlyTs) are the Na+/Cl--dependent plasmalemmal neurotransmitter transporters. GlyTs comprise GlyT1 and GlyT2. They serve to terminate the signaling of glycine by mediating its reuptake from the synaptic cleft…
MCH1R (melanin-concentrating hormone 1 receptor) is one of the melanin-concentrating hormone receptors found in all mammals. What's more, The protein encoded by this gene, a member of the G protein-coupled…
5-HT receptors (Serotonin receptors) are a group of G protein-coupled receptors (GPCRs) and ligand-gated ion channels (LGICs). They mediate both excitatory and inhibitory neurotransmission. The 5-HT receptors modulate the release…
Voltage-gated calcium channels (VGCC) are a group of voltage-gated ion channels in the membrane of excitable cells. Specifically, they have permeability to calcium ion Ca2+. This channel is a key…
D1 and D2 dopamine (DA) receptors play important roles in terms of their neuroanatomical localization and cellular neurobiology. However, any behavioral role for the D4 receptor remains poorly understood. Additionally,…
Dopamine Receptors are a class of G protein-coupled receptors, widely exist in the brain. There are at least five subtypes of dopamine receptors, D1, D2, D3, D4, and D5. The…