Vilanterol (GW642444) is a potent, orally active and long-acting β2-AR (β2-adrenergic receptor) agonist with inherent 24-hour activity. The pEC50s for…
Galectins are β-galactoside-binding proteins. They participate in intracellular trafficking, cell adhesion, and cell–cell signaling. They play a pivotal role in…
Transforming growth factor β (TGFβ) is a pluripotent cytokine in the regulation of various biological processes. Inhibition of TGFβ type…
As we mentioned in our previous blog “ZL0420 is a BRD4 Inhibitor for Blocking TLR3-induced Acute Airway Inflammation”. Diseases characterized…
Bromodomain-containing protein 4 belongs to the family of bromodomain and extra-terminal domain (BET) proteins. The BET family is considered as…