Galectins are β-galactoside-binding proteins. They participate in intracellular trafficking, cell adhesion, and cell–cell signaling. They play a pivotal role in physiological and pathological activities, such as, inflammation, immune response, and…
Transforming growth factor β (TGFβ) is a pluripotent cytokine in the regulation of various biological processes. Inhibition of TGFβ type I receptor offers a novel approach for the treatment of…
As we mentioned in our previous blog “ZL0420 is a BRD4 Inhibitor for Blocking TLR3-induced Acute Airway Inflammation”. Diseases characterized by airway inflammation, excessive airway secretion, and airway obstruction affect…
Bromodomain-containing protein 4 belongs to the family of bromodomain and extra-terminal domain (BET) proteins. The BET family is considered as the most druggable target proteins among Bromodomain-containing proteins (BCPs) for…
Atopic dermatitis (AD), also known as atopic eczema, is a type of inflammation of the skin (dermatitis). The disease typically begins in early childhood, and patients usually develop into atopic…