Parasite Archives - Immune System Research

LXE408 is an Orally Active Proteasome Inhibitor with Anti-leishmaniasis Activity

2020-08-22 Edward Jenner

Proteasomes are protein complexes that degrade unwanted or damaged proteins by proteolysis, which can destroy peptide bonds. Specifically, proteasomes are part of the main mechanism by which cells regulate the…

NPD1335 is a Trypanosoma Brucei Phosphodiesterase B1 Inhibitor

2019-08-22 Edward Jenner

NPD1335 is a Trypanosoma Bruceii Phosphodiesterase B1 Inhibitor 2019 08 22 - NPD1335 is a <i>Trypanosoma Brucei</i> Phosphodiesterase B1 Inhibitor

Trypanosoma brucei (T.b.) rhodesiense and T.b. gambiense are endemic in sub-Saharan Africa. They are typical two causative agents of human African trypanosomiasis (HAT). The drugs for HAT treatment currently on…

Immune System Research

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LXE408 is an Orally Active Proteasome Inhibitor with Anti-leishmaniasis Activity

2020-08-22 Edward Jenner

NPD1335 is a Trypanosoma Brucei Phosphodiesterase B1 Inhibitor

2019-08-22 Edward Jenner