Malaria is a parasitic disease caused by Plasmodium species, which are spread by mosquitoes. The parasites enter the bloodstream through the mosquito's saliva, then live in the liver to develop and…
Antibiotics are antibacterial substances that are active against bacteria. Antibiotics have an effect on treating and preventing such infections. Meanwhile, they can kill or inhibit the growth of bacteria. A…
Trypanosomiasis or trypanosomosis is the name of several diseases in vertebrates caused by parasitic protozoan trypanosomes of the genus Trypanosoma. A number of these diseases occur in animals. Trypanosomiasis in…
PK 11195, a ligand of this protein, acts as an anti-leishmanial agent. At the same time, PK 11195 exhibits IC<sub>50</sub> values of 14.2 μM for L. amazonensis, 8.2 μM for…
Proteasomes are protein complexes that degrade unwanted or damaged proteins by proteolysis, which can destroy peptide bonds. Specifically, proteasomes are part of the main mechanism by which cells regulate the…
Trypanosoma brucei (T.b.) rhodesiense and T.b. gambiense are endemic in sub-Saharan Africa. They are typical two causative agents of human African trypanosomiasis (HAT). The drugs for HAT treatment currently on…