Aplaviroc (AK 602), an SDP derivative, is a potent CCR5 antagonist. Additionally, the IC50s are 0.1-0.4 nM for HIV-1Ba-L, HIV-1JRFL, and…
Protein kinase C (PKC) is a family of protein kinase enzymes with 15 isoforms that can regulate the protein function.…
Serine proteases are the largest class of mammalian proteases. Serine proteases exist in all kingdoms of cellular life as well…
Dihydroorotate dehydrogenase (DHODH), located in the inner membrane of mitochondria, is an iron-containing flavin-dependent enzyme. Using the cofactor ubiquinone, DHODH…
RdRp is a crucial viral enzyme in the life cycle of RNA viruses; hence, it has been targeted in various…