![](https://www.Immune-System-Research.com/"wp-content/uploads"/2022/05/Aplaviroc-IS-A-CCR5-INHIBITOR-2022-0508.png)
Aplaviroc (AK 602), an SDP derivative, is a potent CCR5 antagonist. Additionally, the IC50s are 0.1-0.4 nM for HIV-1Ba-L, HIV-1JRFL, and…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2022/01/Rottlerin-is-a-Specific-PKC-Inhibitor-2022-01-07.jpg)
Protein kinase C (PKC) is a family of protein kinase enzymes with 15 isoforms that can regulate the protein function.…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/12/Camostat-is-an-Orally-Active-Synthetic-Serine-Protease-Inhibitor-2021-12-09.jpg)
Serine proteases are the largest class of mammalian proteases. Serine proteases exist in all kingdoms of cellular life as well…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/11/Brequinar-DUP785-is-a-Potent-DHODH-Inhibitor-2021-11-06.jpg)
Dihydroorotate dehydrogenase (DHODH), located in the inner membrane of mitochondria, is an iron-containing flavin-dependent enzyme. Using the cofactor ubiquinone, DHODH…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/10/Galidesivir-an-Adenosine-Analog-Disrupts-Viral-RdRp-Activity-2021-10-19.jpg)
RdRp is a crucial viral enzyme in the life cycle of RNA viruses; hence, it has been targeted in various…