PI3Kδ belongs to the class I Phosphoinositide 3-kinases (PI3Ks). PI3Kδ plays a critical role in chronic obstructive pulmonary disease (COPD). IHMT-PI3Kδ-372 is a potent and selective PI3Kδ inhibitor for the…
β2-adrenoreceptor is a kind of β-adrenergic receptor across the cell membrane, which binds to adrenaline. Specifically, Adrenaline is a kind of hormone and neurotransmitter and it can enhance the signal…
Matrix metalloproteinases (MMPs) are a family of Zn2+-binding, Ca2+-dependent endopeptidases. They play a prominent role in the physiological and pathological degradation of mammalian extracellular matrix (ECM). The activity of MMPs…