CXCR3 is a G protein-coupled receptor from the CXC chemokine receptor family. It is mainly expressed in immune cells from the lymphoid lineage, including activated T cells. The CXCR3 receptor…
Poly (ADP-ribose) polymerase (PARP) is a family of proteins that participate in many cellular processes, such as DNA repair, genome stability, and programmed cell death. The overactivation of PARP leads…
Coronaviruses are a diverse group of viruses infecting many different animals, and they can cause mild to severe respiratory infections. In 2002 and 2012, respectively, two highly pathogenic coronaviruses with…
Bacteria are small single-celled organisms. Bacteria exist almost everywhere on Earth and are vital to the planet's ecosystems. Some species can live under extreme conditions of temperature and pressure. The…
CXCR3, which belongs to the transmembrane G protein-coupled receptor (GPCR) superfamily, is an inflammatory chemokine receptor. This chemokine receptor can regulate immune cell behavior and promote chemotaxis, cell adhesion as…
Phosphodiesterase (PDE) is any enzyme that breaks a phosphodiester bond. Usually, people speaking of PDE are referring to cyclic nucleotide phosphodiesterase. while, the superfamily of PDE enzymes is classified into…
Tuberculosis, one of the oldest known human diseases, is a potentially serious infectious disease that mainly affects the lungs. It is still one of the major causes of mortality since…
In molecular biology, CD18 (integrin beta chain 2) is an integrin beta chain protein encoded by the human itgb2 gene. Specifically, the lack of CD18 expression can lead to adhesion…
In this article, we will introduce a potent and high-affinity agonist of adenosine A2B receptor, BAY 60-6583. BAY 60-6583 exhibits high affinity by binds to mouse, rabbit, and dog A2BAR…