![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/08/GS143-is-a-Selective-IκBα-Ubiquitination-Inhibitor-2020-09-02.jpg)
GS143 is a selective IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation. Firstly, when GS143…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/05/PF-610355-is-a-Long-Acting-Inhaled-β2-Adrenoreceptor-Agonist-2020-05-23.jpg)
β2-adrenoreceptor is a kind of β-adrenergic receptor across the cell membrane, which binds to adrenaline. Specifically, Adrenaline is a kind…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/05/CAY10471-is-a-Selective-and-Orally-Active-CRTH2-Antagonist-2020-05-06.jpg)
CAY10471 (TM30089) is a potent, selective, and orally active prostaglandin D2 receptor CRTH2 antagonist. In PC12 cells, CAY10471 blocks 15d-PGJ2-induced…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/04/Valategrast-is-an-Orally-Active-Integrin-α4β1-and-α4β7-Antagonist-2020-04-07.jpg)
Asthma is an inflammatory disorder of the airways. Moreover, asthma is a long-term disease of the lungs. The features of…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/09/AZD9898-is-an-Orally-Active-LTC4S-Inhibitor-for-Asthma-Treatment-2019-09-27.jpg)
The arachidonic acid cascade forms a plethora of proinflammatory and pro-resolution lipid metabolites, including prostaglandins, thromboxanes, and leukotrienes. In particular,…