COVID‑19 (Coronavirus disease 2019) is a contagious disease caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Importantly, COVID-19 transmits when infectious particles are breathed in or come…
Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) is a strain of coronavirus that causes COVID-19 (coronavirus disease 2019), the respiratory illness responsible for the COVID-19 pandemic. Although different small-molecule therapeutics…
Coronavirus disease 2019 (COVID-19) has caused a huge threat to global public health. Moreover, the constant emergence of variants of concern (VOCs) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)…
As we all know, the SARS-CoV-1 virus caused the 2002-2004 SARS outbreak. Today, we will introduce a virus -- SARS-CoV-2. SARS-CoV-2 is related to the SARS-CoV-1 virus. SARS-CoV-2 belongs to…
Calcitonin gene-related peptide (CGRP) is a member of the calcitonin peptide family. CGRP has two main forms (α And β). Specifically, CGRP is a highly effective vasodilator. It is important…
SARS‑CoV‑2 (Severe acute respiratory syndrome coronavirus 2) is a strain of coronavirus. However, SARS‑CoV‑2 has caused on going COVID-19 (coronavirus disease 2019) pandemic and led to a serious threat to…
SARS-CoV-2 PLpro (SARS-CoV-2 papain-like protease) is the largest of the SARS-CoV-2 non-structural proteins (212 kDa). Importantly, the amino acid sequence of SARS-CoV-2PLpro is 98 % identical to related proteases from bat coronaviruses BANAL-52…
MASP-2 (Mannan-binding lectin-associated serine protease-2) is a key serine protease in the lectin pathway of complement activation, resulting in excessive complement activation by potentiating MBL-dependent MASP-2 activation, and the deposition…
Coronaviruses are a diverse group of viruses infecting many different animals, and they can cause mild to severe respiratory infections. In 2002 and 2012, respectively, two highly pathogenic coronaviruses with…
SARS-COV-2 is a positive-sense single-stranded RNA coronavirus. This virus can cause severe acute respiratory syndrome and spreads between people through aerosols and respiratory droplets. It broke out in early 2020,…