T-26c, A Highly Selective MMP-13 Inhibitor
The matrix metalloproteinases (MMPs) are a family of zincdependent enzymes involved in the degradation and remodeling of extra-cellular matrix. There are a large number of potent MMP inhibitors on the…
The matrix metalloproteinases (MMPs) are a family of zincdependent enzymes involved in the degradation and remodeling of extra-cellular matrix. There are a large number of potent MMP inhibitors on the…
Thuja orientalis is extensively used as an herbal medicine in Korea and China. It is used for treating conditions such as gout, rheumatism, diarrhoea and chronic tracheitis. It is one…
Atopic dermatitis (AD), also known as atopic eczema, is a type of inflammation of the skin (dermatitis). The disease typically begins in early childhood, and patients usually develop into atopic…
Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase. ALK belongs to the insulin receptor kinase subfamily. Nucleophosmin (NPM)-ALK is a fusion protein. NPM-ALK fusion protein expresses in the majority…
Mycobacteria cause a variety of human diseases, including tuberculosis (TB), leprosy, Buruli ulcer, and pulmonary nontuberculous mycobacterial disease. WHO reported that more than 10 million people were infected with TB…
TNF alpha is a cell signaling protein involved in systemic inflammation. It is one of the cytokines that make up the acute phase reaction. TNF alpha promotes inflammation and its…
Integrins are cell surface protein receptors with α and β subunits. They participate in multiple cellular functions such as adhesion and anchoring to extracellular matrix, transducing growth factor signals. Emerging…
Type 2 diabetes mellitus (T2DM) is a progressive disease. The type 2 Diabetes is accompanied by an increase in diabetic complications, such as diabetic nephropathy. Diabetic nephropathy is the leading…