Darapladib is a Potent Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2)
Darapladib (SB-480848) is a potent, selective, freely reversible, non-covalently bound, orally active inhibitor of Lp-PLA2 with an IC50 of 0.25 nM, and it serves as a predictive biomarker of inflammation in cardiovascular…