The α-amino-3-hydroxy-5-methyl-4-isoxazolopropionic acid receptor (AMPA receptor) is an ionic glutamate (iGluR) transmembrane receptor. Specifically, it can mediate the rapid synaptic transmission system in the central nervous system. AMPAR, together with…
Glutamate is a predominant neurotransmitter released from excitatory neurons related to the fast synaptic excitation. The released glutamates diffuse across the synaptic cleft and generate fast EPSPs through binding to…
Anticonvulsants are a diverse group of pharmacological agents used in the treatment of epileptic seizures. Broad-spectrum anticonvulsants are of considerable interest as antiepileptic drugs. In this study, researchers identified promising…