![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/12/Rolipram-is-a-Selective-Phosphodiesterases-PDE4-Inhibitor-2021-12-03.jpg)
Phosphodiesterases (PDEs) are enzymes that convert cyclic nucleotides (cAMP and cGMP) to their corresponding 5′-AMP and 5′-GMP in order to…
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Nociceptin/orphanin FQ (N/OFQ) is a neuropeptide that selectively interacts with the NOP receptor. NOP receptor is a member of the…
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Major depressive disorder (MDD) is a chronic illness. And it affects ~17% of the population and one leading cause of…
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Phosphodiesterase 4 (PDE4) is an enzyme mainly expresses in the central nervous system, smooth muscle, cardiovascular. In neuronal cells, PDE4…