Skip to content

Immune System Research

Up to date immunology information

Immune System Research

Up to date immunology information

  • Home
    • Home
    • Antimalarial
Infection Malaria

WM382 is an Orally Active Plasmepsin IX/X Inhibitor with Antimalarial Activity

Edward Jenner 2022-12-01

Malaria is a parasitic disease caused by Plasmodium species, which are spread by mosquitoes. Erythrocytes are the replicating factories for malaria parasites. There are three malarial life-cycle stages: exoerythrocytic forms, asexual…

Cancer Immunology Inflammation Malaria

Manzamine A, an Orally Active β-carboline Alkaloid, Inhibits GSK-3β and CDK-5

Edward Jenner 2021-07-29

Glycogen synthase kinase-3 (GSK-3) is a serine-threonine kinase ubiquitously expressed and involved in the regulation of many cell functions. GSK-3 phosphorylates the microtubule-associated protein tau in mammalian cells. This hyperphosphorylation…

Malaria Parasite

DSM705 is a Plasmodium DHODH Inhibitor

Edward Jenner 2021-06-30

Malaria is one of the most widespread and ancient infectious diseases of humanity. In particular, Dihydroorotate dehydrogenase (DHODH) acts as a target for the development of new antimalarials. In addition,…

Malaria

FNDR-20123 is an Orally Active and a First-in-Class Anti-Malarial HDAC Inhibitor

Edward Jenner 2021-03-20

Malaria remains one of the most severe and life-threatening infectious diseases. Among the various Plasmodium spp., Plasmodium falciparum is the most virulent and life-threatening form, prevailing in Southeast Asia and Africa.…

Malaria Parasite

SJ000025081, a Dihydropyridine, Acts as a Potent Antimalarial Agent

Edward Jenner 2020-10-17

Malaria is a mosquito-borne infectious disease that affects humans and other animals. Specifically, malaria caused Symptoms usually including fever, fatigue, vomiting and headache. Besides, malaria is due to the single-celled…

Malaria Parasite

AN3661, an Antimalarial Agent, is a PfCPSF3 Inhibitor

Edward Jenner 2020-06-11

Cleavage and polyadenylation specificity factor (CPSF) is relevant to the cleavage of the 3' signaling region from a newly synthesized pre-messenger RNA (pre-mRNA) molecule. Specifically, it is in the process…

Malaria Parasite

TCMDC-135051, a Highly Selective PfCLK3 Inhibitor, Has Potential to Treat Malaria

Edward Jenner 2019-09-20

PfCLK3 is a protein kinase essential for maintaining the asexual blood stage of both P. falciparum and P. berghei.  In mammalian cells, the CLK protein kinase family and the closely related SRPK family…

Cancer Immunology Immune Checkpoint Parasite

RRx-001 is a Dual Checkpoint Inhibitor by Downregulating CD47 and SIRP-α

Edward Jenner 2019-09-08

As previously introduced, we all have known that RRx-001, a hypoxia-selective epigenetic agent and a radio- and chem-sensitizer. Additionally, it triggers apoptosis and overcomes drug resistance in myeloma. RRx-001 exhibits…

Malaria Updated

CWHM-1552 is an Orally Acitive Antimalarial Compound

Edward Jenner 2019-07-25

Malaria has been a military problem throughout history capable of causing epidemics that stop military operations. Particularly, malaria has had a greater impact on world history than any other infectious…

Parasite

BRD9185 is a DHODH Inhibitor with Antimalarial Activity

Edward Jenner 2019-06-13

In our previous blogs, we have introduced two compounds that have antimalarial activity, BDA-410 and UCT943. BDA-410 is a calpain inhibitor and UCT943 is an inhibitor of Plasmodium PI4K. Today,…

Posts navigation

1 2

Next Page »

Recent Posts

  • PRX-08066 is an orally active 5-HT2BR Antagonist with Vasodilation Effect for PAH
  • Apocynin is a NADPH oxidase (NOX) Inhibitor for Metabolic and Inflammation Research
  • Xylometazoline is an α-adrenergic Receptor Agonist for Nose Stuffiness Research
  • Elafibranor is a PPARα/δ Agonist for Metabolic Disease Research
  • Doravirine is a HIV-1 Inhibitor for Infection Research

Archives

  • September 2023
  • August 2023
  • July 2023
  • June 2023
  • May 2023
  • April 2023
  • March 2023
  • February 2023
  • January 2023
  • December 2022
  • November 2022
  • October 2022
  • September 2022
  • August 2022
  • July 2022
  • June 2022
  • May 2022
  • April 2022
  • March 2022
  • February 2022
  • January 2022
  • December 2021
  • November 2021
  • October 2021
  • September 2021
  • August 2021
  • July 2021
  • June 2021
  • May 2021
  • April 2021
  • March 2021
  • February 2021
  • January 2021
  • December 2020
  • November 2020
  • October 2020
  • September 2020
  • August 2020
  • July 2020
  • June 2020
  • May 2020
  • April 2020
  • March 2020
  • February 2020
  • January 2020
  • December 2019
  • November 2019
  • October 2019
  • September 2019
  • August 2019
  • July 2019
  • June 2019
  • May 2019
  • April 2019
  • March 2019
  • January 2019

Categories

  • Abdominal Aortic Aneurysm
  • Acanthosis
  • Achondroplasia
  • Acute Pancreatitis
  • Acute Radiation Syndrome
  • AIDs
  • Airway Immunology
  • Airway Inflammation
  • Allergy
  • Alzheimer
  • Alzheimer's disease
  • Analgesia
  • Anemia
  • antibiotic
  • Antibodydrug
  • anticonvulsant
  • Antigen-Induced Arthritis
  • Arterial Thrombosis
  • Arthritis
  • Asthma
  • Asthma
  • Atherosclerosis
  • Atopic Dermatitis
  • Atopic Dermatitis
  • Atopic dermatitis (AD)
  • Atrial Fibrillation
  • Autism
  • Auto-Inflammatory
  • Autoimmune diseases
  • Autoimmune Disorders
  • Autoimmune Encephalitis
  • Autoimmune Encephalomyelitis
  • Bacterial
  • Bronchial Airway Infection
  • Cancer
  • Cancer Immunology
  • Cancer Immunotherapy
  • Cardiovascular
  • Chemokines
  • Chronic Arthritis
  • Chronic endemic diseases
  • Chronic Heart Failure
  • Chronic Hepatitis B
  • Chronic kidney disease
  • Chronic Liver Disease
  • Chronic lymphocytic leukemia (CLL)
  • Chronic Obstructive Pulmonary Disease
  • Chronic Obstructive Pulmonary Disease
  • Chronic obstructive pulmonary disease (COPD)
  • Chronic Urticaria
  • Cognitive Disorders
  • Colitis
  • Collagen-Induced Arthritis
  • Complement System
  • Coronavirus
  • Crohn's Disease
  • Degenerative disease
  • Diabetes
  • Diabetes
  • Diabetic Complication
  • Dilated cardiomyopathy disease
  • DNV
  • Dye
  • EMCV
  • Encephalomyelitis
  • Encephalomyelitis
  • Endocrinology
  • Endometriosis
  • Enterovirus
  • Epilepsy
  • Fabry Disease
  • Fibrosis
  • FIPV
  • Fungal
  • Fungal
  • glioblastoma
  • Graves' hyperthyroidism
  • Growth & Development
  • Haemophilia
  • HBV
  • HCV
  • Heart Failure
  • Hemorrhagic Disorder
  • Hepatic steatosis
  • Hepatic steatosis
  • Hepatitis
  • Hepatitis
  • Hepatitis C Virus
  • Hereditary Angioedema
  • HIV
  • Homeostasis
  • Hot flushes
  • HPV
  • HSV
  • hypertension
  • Idiopathic Pulmonary Fibrosis
  • Immune
  • Immune Checkpoint
  • Immune homeostasis
  • Immune Rejection
  • Immunity
  • Immunodeficiency
  • Immunology
  • Immunotherapy
  • Infection
  • Inflammation
  • Inflammatory
  • Influenza Virus
  • Innate Immune
  • Intestinal Inflammation
  • Ischemia
  • Ischemic stroke
  • Kidney Fibrosis
  • Kidney immune
  • Kidney Injury
  • Liver fibrosis
  • Lower Respiratory Infection
  • Lung Inflammation
  • Lupus Nephritis
  • lymphoma tumor
  • Malaria
  • Mesothelioma
  • Metabolic Disease
  • Metabolic Disorder
  • migraine
  • Multiple Sclerosis
  • Multiple Sclerosis
  • Myelodysplastic Syndromes
  • NAFLD
  • NASH
  • Neuroimmunology
  • Neurological Disease
  • Nociceptive
  • obesity
  • Osteoarthritis
  • Osteoporosis
  • Pancreatitis
  • Pancreatitis
  • Parasite
  • Parasite
  • Parkinson's disease
  • Parkinson’s
  • Patchy hair loss
  • Periodontitis
  • Peritonitis
  • Psoriasis
  • Psoriasis
  • Pulmonary Arterial Hypertension (PAH)
  • Pulmonary Fibrosis
  • RABV
  • RABV
  • Renal Fibrosis
  • Respiratory Infection
  • Retinal Vascular Disease
  • Retinal Vascular Diseases
  • Retinopathy
  • Rett Syndrome
  • Rheumatoid Arthritis
  • Rheumatoid Arthritis
  • Rhinitis
  • Rhinovirus
  • SARS
  • SARS-CoV
  • SARS-CoV-2
  • Schizophrenia
  • Schizophrenia
  • Seizure
  • Sepsis
  • Skin Inflammation
  • Stroke
  • Systemic Inflammatory Response Syndrome
  • Systemic Lupus Erythematosus
  • Systemic Scleroderma
  • T2DM
  • Thrombosis
  • Tuberculosis
  • Type 2 Diabetes Mellitus
  • Type 2 Diabetes Mellitus
  • Ulcerative Colitis
  • Uncategorized
  • Updated
  • Venous Ulcers
  • Viral Immunology

You Missed

Pulmonary Arterial Hypertension (PAH)

PRX-08066 is an orally active 5-HT2BR Antagonist with Vasodilation Effect for PAH

Cancer Immune Metabolic Disease

Apocynin is a NADPH oxidase (NOX) Inhibitor for Metabolic and Inflammation Research

Uncategorized

Xylometazoline is an α-adrenergic Receptor Agonist for Nose Stuffiness Research

NASH obesity

Elafibranor is a PPARα/δ Agonist for Metabolic Disease Research

Immune System Research

Up to date immunology information

Copyright © All rights reserved | Blogus by Themeansar.