Neuropilin-1 (NRP1) is a membrane-bound co-receptor of the tyrosine kinase receptor, which can be used for vascular endothelial growth factor and signal protein family members. Specifically, NRP1 plays a variety…
CXC chemokine receptors are the complete membrane proteins and they can specifically bind and respond to CXC chemokine family cytokines. Specifically, they represent a subfamily of chemokine receptors, a large…
Tumor angiogenesis plays an essential role in carcinogenesis, cancer progression, and metastasis. The inflammation is a key feature of the environment within and around tumors. Some studies indicate that the…
As we all know, Farnesyl diphosphate synthase(FPPS) is an important drug target for bone resorption, cancer, and some infectious diseases. Besides, FPPS and undecaprenyl diphosphate synthase (UPPS) involves in bacterial…
Spleen tyrosine kinase (Syk) is a non-receptor tyrosine kinase. Syk plays an important role in allergic diseases and inflammation. Thus, Syk is an attractive target for therapeutic kinase inhibitors. This…