B Cell Archives - Immune System Research

GNE-1858 is an ATP-competitive Hematopoietic Progenitor Kinase-1 (HPK1) Inhibitor

2020-04-21 Edward Jenner

Hematopoietic progenitor kinase-1 (HPK1) is a serine/threonine Ste20 related protein kinase. It expresses only in hematopoietic cells (such as T cells, B cells, and dendritic cells). Specifically, HPK1 is a…

SPL-410 is an Orally Active SPPL2a Inhibitor

2019-08-01 Edward Jenner

The immune system is a powerful host defense mechanism specializing in antigen recognition. Besides, loss of tolerance to self-antigens results in pathological conditions which are manifested as autoimmune diseases. Moreover,…

Immune System Research

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GNE-1858 is an ATP-competitive Hematopoietic Progenitor Kinase-1 (HPK1) Inhibitor

2020-04-21 Edward Jenner

SPL-410 is an Orally Active SPPL2a Inhibitor

2019-08-01 Edward Jenner