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Tag: BET BD2

GSK620 is a Potent and Orally Active pan-BET-BD2 Inhibitor

2021-01-08 Edward Jenner

The therapeutic potential of extra terminal domain inhibitor (iBET) has increasing studies both in oncology and immunoinflammatory. Moreover, iBETs are…

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Posted in: Arthritis, Hepatitis, Inflammation, Psoriasis Filed under: Anti-Inflammatory, BET BD2, BRD4, Psoriasis

RVX-297 is an Orally Bioavailable and Selective BET BD2 Inhibitor

2020-07-22 Edward Jenner

Proinflammatory stimuli induce rapid transcriptional responses. They are essential for host defense from infection. An inflammatory response involves a variety…

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Posted in: Arthritis, Autoimmune Disorders, Collagen-Induced Arthritis, Inflammation Filed under: BET BD2, Bromodomain, IL-6

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