The therapeutic potential of extra terminal domain inhibitor (iBET) has increasing studies both in oncology and immunoinflammatory. Moreover, iBETs are actively progressing in the clinic for oncology indications. Nevertheless, there…
HIV integrates its provirus into the host genome and establishes latent infection. Antiretroviral therapy (ART) can effectively suppress active HIV replication. But, it cannot eradicate or cure the virus. Host…
NF-κB-mediated inflammation is a major pathology in kidney diseases, such as non-kidney inflammatory diseases, and rheumatoid arthritis. HIV infection in the kidney induces NF-κB activation, leading to the production of…