![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/08/4-Hydroxytamoxifen-is-an-Orally-Active-Selective-Estrogen-Receptor-Modulator-SERM-2021-08-31.jpg)
Selective estrogen receptor modulator (SERM) is a kind of drugs that act on estrogen receptor (ER). Specifically, they act as…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/08/Trabectedin-Ecteinascidin-743-is-a-Tetrahydroisoquinoline-Alkaloid-with-Antitumor-Activity-2021-08-27.jpg)
Apoptosis is a form of programmed cell death in multicellular organisms. Specifically, apoptotic signals help to protect genomic integrity, and…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/07/ON1231320-is-a-Highly-Specific-PLK2-Inhibitor-2021-07-13.jpg)
Polo-like kinases (PLKs) have numerous roles in both mitosis and meiosis, including functions related to chromosome segregation, cohesin removal, and…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/01/SBP-7455-is-an-Orally-Active-Dual-ULK1-ULK2-Autophagy-Inhibitor-2020-01-23.jpg)
Autophagy is a multi-step pathway initiated through the ULK preinitiation complex, which consists of unc-51-like autophagy activating kinase 1 (ULK1)…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2021/01/Neratinib-is-an-Orally-Available-Irreversible-Tyrosine-Kinase-Inhibitor-2020-01-19.jpg)
Neratinib is an irreversible tyrosine kinase inhibitor with IC50s of 59 nM and 92 nM for HER2 and EGFR, respectively.…