![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/11/MKI-1-an-MASTL-Inhibitor-Exerts-Antitumor-and-Radiosensitizer-Activities-2020-12-01.jpg)
Mitosis is an attractive target for selective anticancer treatment. Mitotic kinases, including CDKs, AURKs, and PLK1, associate with tumor progression and prognosis.…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/11/BETd-246-is-a-PROTAC-Based-BET-BRD-Degrader-2020-11-12.jpg)
In previous blogs, we have introduced a lot of PROTAC based degraders, including TD-428, HJB97, A1874, etc. Coincidentally most of…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2020/09/OP-5244-is-a-Potent-and-Orally-Bioavailable-CD73-Inhibitor-2020-10-13.jpg)
CD73, also known as 5′-nucleotidase (5′-NT), is commonly used to convert amp to adenosine. Specifically, CD73 is a surface enzyme…