CRTH2 Archives - Immune System Research

AT-56 is a Selective and Orally Active Inhibitor of Lipocalin-type prostaglandin D synthase (L-PGDS)

2020-08-06 Edward Jenner

Prostaglandin D2 (PGD2) is a major inflammatory mediator produced by mast cells and Th2 cells. PGD2 is a lipid mediator involved in sleep and inflammatory responses. Besides, PGD2 activates two…

CAY10471 is a Selective and Orally Active CRTH2 Antagonist

CAY10471 (TM30089) is a potent, selective, and orally active prostaglandin D2 receptor CRTH2 antagonist. In PC12 cells, CAY10471 blocks 15d-PGJ2-induced p38 MAP kinase activation and decreases phosphorylation of p-38 MAP…

Immune System Research

Up to date immunology information.

Browsed by
Tag: CRTH2

AT-56 is a Selective and Orally Active Inhibitor of Lipocalin-type prostaglandin D synthase (L-PGDS)

2020-08-06 Edward Jenner

CAY10471 is a Selective and Orally Active CRTH2 Antagonist

2020-05-07 Edward Jenner