Toll-like receptors 7 and 8 (TLR7/8) are receptors for single-stranded RNA that reside in the endosome. TLR8 mainly expresses in…
Rheumatoid arthritis (RA) is a kind of destructive systemic autoimmune disease. Many different inflammatory cells invade the joint synovium. In…
3M-011 is a potent dual toll-like receptor TLR7/8 agonist and a cytokine inducer. Firstly, in B16-F10 melanoma cells, 3M-011 treatment can decrease…
Protein–protein interactions are major regulators of cell biology and important targets in drug discovery. Specifically, protein-protein interactions are driven by…
FBXOs (F-box proteins) is an F-box domain-containing proteins, mediate protein-protein interactions. They play a role in cellular functions, like signal…