TPCA-1, a Selective IKK-2 Inhibitor, Alleviates Rheumatoid Arthritis
IκB kinase 2 (IKK-2) plays a pivotal role in the nuclear factor-κB-regulated production of proinflammatory molecules by stimuli, such as tumor necrosis factor (TNF)-αand interleukin (IL)-1. Thus, inhibition of IKK-2…