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Tag: Exosome

DPTIP is a Brain Penetrant N-SMase 2 and Exosome Inhibitor

2020-09-12 Edward Jenner

Neutral sphingomyelinase 2 (nSMase2) catalyzes the formation and release of extracellular vesicles (EVs) . Human nSMase2 catalyzes the hydrolysis of…

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Posted in: Inflammation Filed under: Exosome, IL-1β, N-SMase

Neticonazole is a Long-Acting Antifungal Agent and an Orally Active Exosome Secretion Inhibitor

2020-04-09 Edward Jenner

Exosomes act as vesicles of endosomal origin secreted from reticulocytes. Exosomes bear proteins, lipids, and RNAs, mediating intercellular communication between…

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Posted in: Fungal, Infection Filed under: Anti-Tumor, Exosome, Long-Acting
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