Exosome Archives - Immune System Research

DPTIP is a Brain Penetrant N-SMase 2 and Exosome Inhibitor

2020-09-12 Edward Jenner

Neutral sphinghomyelinase 2 (nSMase2) catalyzes the formation and release of extracellular vesicles (EVs) . Human nSMase2 catalyzes the hydrolysis of sphingomyelin to phosphorylcholine and ceramide. DPTIP, a potent brain penetrant…

Neticonazole is a Long-Acting Antifungal Agent and an Orally Active Exosome Secretion Inhibitor

2020-04-09 Edward Jenner

Exosomes act as vesicles of endosomal origin secreted from reticulocytes. Exosomes bear proteins, lipids, and RNAs, mediating intercellular communication between different cell types in the body, and thus affecting normal…

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DPTIP is a Brain Penetrant N-SMase 2 and Exosome Inhibitor

2020-09-12 Edward Jenner

Neticonazole is a Long-Acting Antifungal Agent and an Orally Active Exosome Secretion Inhibitor

2020-04-09 Edward Jenner