![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/12/SPR741-an-Anti-biotic-Potentiator-Inhibits-Multidrug-Resistant-Gram-negative-Bacteria-2019-12-16.jpg)
SPR741, an antibiotic adjuvant that can permeabilize the Gram-negative membrane. In this article, we will briefly introduce this compound in…
![](https://www.Immune-System-Research.com/"wp-content/uploads"/2019/10/ACHN-975-is-a-First-in-class-and-Selective-LpxC-Inhibitor-2019-10-21.jpg)
The bacterial enzyme UDP-3-O-[(R)-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase (LpxC) catalyzes the first committed step of lipid A biosynthesis. Additionally, the process represents a…