SPR741, an antibiotic adjuvant that can permeabilize the Gram-negative membrane. In this article, we will briefly introduce this compound in…
The bacterial enzyme UDP-3-O-[(R)-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase (LpxC) catalyzes the first committed step of lipid A biosynthesis. Additionally, the process represents a…