Narsoplimab (OMS 721) is an IgG4 mAb That Binds MASP-2 and Blocks Lectin Pathway Activation
MASP-2 (Mannan-binding lectin-associated serine protease-2) is a key serine protease in the lectin pathway of complement activation, resulting in excessive complement activation by potentiating MBL-dependent MASP-2 activation, and the deposition…